diff --git a/README.md b/README.md
index 214f1aaa..b50803ea 100644
--- a/README.md
+++ b/README.md
@@ -27,7 +27,7 @@ To further configure your plugin, use the following custom parameters in your `s
 
 | Parameter                     | Description                                                                                                                                                                                                                                                                                                                                                                                                                  |
 | ----------------------------- |------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------|
-| `site`                        | Set which Datadog site to send data to, such as `datadoghq.com` (default), `datadoghq.eu`, `us3.datadoghq.com`, `us5.datadoghq.com`, `ap1.datadoghq.com`, `ap2.datadoghq.com`, or `ddog-gov.com`. This parameter is required when collecting telemetry using the Datadog Lambda Extension.                                                                                                                                                        |
+| `site`                        | Set which Datadog site to send data to, such as `datadoghq.com` (default), `datadoghq.eu`, `us3.datadoghq.com`, `us5.datadoghq.com`, `ap1.datadoghq.com`, `ap2.datadoghq.com`, `ddog-gov.com`, or `us2.ddog-gov.com`. This parameter is required when collecting telemetry using the Datadog Lambda Extension.                                                                                                                                                        |
 | `apiKey`                      | [Datadog API key][7]. This parameter is required when collecting telemetry using the Datadog Lambda Extension. Alternatively, you can also set the `DATADOG_API_KEY` environment variable in your deployment environment.                                                                                                                                                                                                    |
 | `appKey`                      | Datadog app key. Only needed when the `monitors` field is defined. Alternatively, you can also set the `DATADOG_APP_KEY` environment variable in your deployment environment.                                                                                                                                                                                                                                                |
 | `apiKeySecretArn`             | An alternative to using the `apiKey` field. The ARN of the secret that is storing the Datadog API key in AWS Secrets Manager. Remember to add the `secretsmanager:GetSecretValue` permission to the Lambda execution role.                                                           |
diff --git a/src/index.spec.ts b/src/index.spec.ts
index ffdfeb7e..fecea80a 100644
--- a/src/index.spec.ts
+++ b/src/index.spec.ts
@@ -803,7 +803,7 @@ describe("ServerlessPlugin", () => {
       }
       expect(threwError).toBe(true);
       expect(thrownErrorMessage).toEqual(
-        "Warning: Invalid site URL. Must be one of datadoghq.com, datadoghq.eu, us3.datadoghq.com, us5.datadoghq.com, ap1.datadoghq.com, ap2.datadoghq.com, ddog-gov.com.",
+        "Warning: Invalid site URL. Must be one of datadoghq.com, datadoghq.eu, us3.datadoghq.com, us5.datadoghq.com, ap1.datadoghq.com, ap2.datadoghq.com, ddog-gov.com, us2.ddog-gov.com.",
       );
     });
 
diff --git a/src/index.ts b/src/index.ts
index cf780960..3f1ec6ff 100644
--- a/src/index.ts
+++ b/src/index.ts
@@ -640,6 +640,7 @@ function validateConfiguration(config: Configuration): void {
     "ap1.datadoghq.com",
     "ap2.datadoghq.com",
     "ddog-gov.com",
+    "us2.ddog-gov.com",
   ];
   if (!config.testingMode && config.site !== undefined && !siteList.includes(config.site.toLowerCase())) {
     throw new Error(`Warning: Invalid site URL. Must be one of ${siteList.join(", ")}.`);