diff --git a/modules/openapi-generator/src/main/resources/python/api_client.mustache b/modules/openapi-generator/src/main/resources/python/api_client.mustache
index f3c27f2b8f1e..e89b61173a74 100644
--- a/modules/openapi-generator/src/main/resources/python/api_client.mustache
+++ b/modules/openapi-generator/src/main/resources/python/api_client.mustache
@@ -420,7 +420,7 @@ class ApiClient:
                 data = json.loads(response_text)
             except ValueError:
                 data = response_text
-        elif re.match(r'^application/(json|[\w!#$&.+-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
+        elif re.match(r'^application/(json|[\w!#$&.+\-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
             if response_text == "":
                 data = ""
             else:
diff --git a/samples/client/echo_api/python-disallowAdditionalPropertiesIfNotPresent/openapi_client/api_client.py b/samples/client/echo_api/python-disallowAdditionalPropertiesIfNotPresent/openapi_client/api_client.py
index 513b1d158a35..4989e8ce0944 100644
--- a/samples/client/echo_api/python-disallowAdditionalPropertiesIfNotPresent/openapi_client/api_client.py
+++ b/samples/client/echo_api/python-disallowAdditionalPropertiesIfNotPresent/openapi_client/api_client.py
@@ -412,7 +412,7 @@ def deserialize(self, response_text: str, response_type: str, content_type: Opti
                 data = json.loads(response_text)
             except ValueError:
                 data = response_text
-        elif re.match(r'^application/(json|[\w!#$&.+-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
+        elif re.match(r'^application/(json|[\w!#$&.+\-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
             if response_text == "":
                 data = ""
             else:
diff --git a/samples/client/echo_api/python/openapi_client/api_client.py b/samples/client/echo_api/python/openapi_client/api_client.py
index 513b1d158a35..4989e8ce0944 100644
--- a/samples/client/echo_api/python/openapi_client/api_client.py
+++ b/samples/client/echo_api/python/openapi_client/api_client.py
@@ -412,7 +412,7 @@ def deserialize(self, response_text: str, response_type: str, content_type: Opti
                 data = json.loads(response_text)
             except ValueError:
                 data = response_text
-        elif re.match(r'^application/(json|[\w!#$&.+-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
+        elif re.match(r'^application/(json|[\w!#$&.+\-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
             if response_text == "":
                 data = ""
             else:
diff --git a/samples/openapi3/client/petstore/python-aiohttp/petstore_api/api_client.py b/samples/openapi3/client/petstore/python-aiohttp/petstore_api/api_client.py
index 7ce51c480c26..927bdea1e489 100644
--- a/samples/openapi3/client/petstore/python-aiohttp/petstore_api/api_client.py
+++ b/samples/openapi3/client/petstore/python-aiohttp/petstore_api/api_client.py
@@ -414,7 +414,7 @@ def deserialize(self, response_text: str, response_type: str, content_type: Opti
                 data = json.loads(response_text)
             except ValueError:
                 data = response_text
-        elif re.match(r'^application/(json|[\w!#$&.+-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
+        elif re.match(r'^application/(json|[\w!#$&.+\-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
             if response_text == "":
                 data = ""
             else:
diff --git a/samples/openapi3/client/petstore/python/petstore_api/api_client.py b/samples/openapi3/client/petstore/python/petstore_api/api_client.py
index 33d7dde63b87..a06ecfa5b50f 100755
--- a/samples/openapi3/client/petstore/python/petstore_api/api_client.py
+++ b/samples/openapi3/client/petstore/python/petstore_api/api_client.py
@@ -411,7 +411,7 @@ def deserialize(self, response_text: str, response_type: str, content_type: Opti
                 data = json.loads(response_text)
             except ValueError:
                 data = response_text
-        elif re.match(r'^application/(json|[\w!#$&.+-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
+        elif re.match(r'^application/(json|[\w!#$&.+\-^_]+\+json)\s*(;|$)', content_type, re.IGNORECASE):
             if response_text == "":
                 data = ""
             else:
diff --git a/samples/openapi3/client/petstore/python/tests/test_deserialization.py b/samples/openapi3/client/petstore/python/tests/test_deserialization.py
index c8ae1a90c77d..a8ebc21126cd 100644
--- a/samples/openapi3/client/petstore/python/tests/test_deserialization.py
+++ b/samples/openapi3/client/petstore/python/tests/test_deserialization.py
@@ -342,5 +342,7 @@ def test_deserialize_content_type(self):
 
         with self.assertRaises(petstore_api.ApiException) as cm:
             deserialized = self.deserialize(response, "Dict[str, str]", 'application/jsonnnnn')
-        
+
+        with self.assertRaises(petstore_api.ApiException) as cm:
+            deserialized = self.deserialize(response, "Dict[str, str]", 'application/<+json')